Yes. Proteus simulates the sensor at the I2C bus level. Any MCU with I2C support will work.
Most MAX30100 Proteus models do not simulate dynamic PPG signals. They provide register-level I2C simulation. You may need to inject test data using a stimulus script in Proteus. max30100 proteus library download
Proteus Professional, developed by Labcenter Electronics, is one of the most popular simulation software packages for microcontroller-based designs. Unfortunately, the software’s default component library does not include the MAX30100 sensor. This gap leads to the most searched query among simulation enthusiasts: developed by Labcenter Electronics